TOP1 antibody

References #2
Category:
Catalogue No.: 
FNab09823
Alias: 
DNA topoisomerase 1|DNA topoisomerase I|TOP1 antibody
Gene Name: 
TOP1
UniProt ID: 
P11387
Size Price
100μg Inquiry
Dispatch Time: About 3 working days
Contact Us
Product Name
TOP1 antibody
Catalogue No.
FNab09823
Gene Name
TOP1
UniProt ID
P11387
Alias
DNA topoisomerase 1|DNA topoisomerase I|TOP1 antibody
Isotype
IgG
Form
liquid
Purification
Immunogen affinity purified
Immunogen
topoisomerase (DNA) I
Recommended dilution
WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IP: 1:50 - 1:100
Purity
≥95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Background
This gene encodes a DNA topoisomerase, an enzyme that controls and alters the topologic states of DNA during transcription. This enzyme catalyzes the transient breaking and rejoining of a single strand of DNA which allows the strands to pass through one another, thus altering the topology of DNA. This gene is localized to chromosome 20 and has pseudogenes which reside on chromosomes 1 and 22.


Figures for this product are not available in this catalogue.

Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Dispatch Time
About 3 working days
Ordering & Delivery
How do I place an order?
Use the Inquiry button on this page or write to tekintolga89@gmail.com. Include the catalogue number and the quantity you need.
What is the dispatch time?
In-stock items are dispatched within 1-3 business days. Items that need to be produced take longer; we confirm the date when you order.
Do you ship outside Türkiye?
Shipping is arranged case by case. Contact us with the destination and we will quote carriage and lead time.
Storage & Handling
How should an unopened kit be stored?
At 2-8 °C unless the datasheet says otherwise. Do not freeze a kit that is not marked for freezing.
How long is an opened kit stable?
It depends on the component. The Kit Components table on this page lists the storage condition for each item after opening.
What should I do if the shipment arrives warm?
Photograph the package and contact us the same day. Do not use the kit until we have confirmed it is still within specification.
Assay Questions
Which sample types can I use?
The Sample Type row in the specifications above lists the validated matrices for this product. Other matrices need validation on your side.
My background is too high. What should I check?
The usual causes are insufficient washing, contaminated buffers, or too much detection antibody. Our Protocol pages cover the full troubleshooting sequence.
Can I run fewer wells than the kit provides?
Yes. Dismountable microplates let you use part of a plate and reseal the rest with the desiccant supplied.
Technical Support
Something did not work. What do you need from me?
Send the catalogue number, the lot, your protocol deviations and the raw OD values. That is usually enough to identify the cause.
Do you provide a certificate of analysis?
Yes, per lot. Ask for it with the catalogue number and lot number.

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Cited Publications (2)

Validating TDP1 as an Inhibition Target for Lipophilic Nucleoside Derivative in Human Cells IF: 4.9

International Journal of Molecular Sciences · 2025-10-31

Co-delivery Liposomes of Irinotecan Hydrochloride and Curcumin in the Synergistic Treatment of Colorectal Cancer IF: 4.5

Journal of Drug Delivery Science and Technology · 2024-07-05

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