NMNAT1 antibody

References #1
Category:
Catalogue No.: 
FNab05767
Alias: 
Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 1 (NMN/NaMN adenylyltransferase 1)|Nicotinamide-nucleotide adenylyltransferase 1 (NMN adenylyltransferase 1)|Nicotinate-nucleotide adenylyltransferase 1 (NaMN adenylyltransferase 1)|NMNAT1|NMNAT antibody
Gene Name: 
NMNAT1
UniProt ID: 
Q9HAN9
Size Price
100μg Inquiry
Dispatch Time: About 3 working days
Contact Us
Product Name
NMNAT1 antibody
Catalogue No.
FNab05767
Gene Name
NMNAT1
UniProt ID
Q9HAN9
Alias
Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 1 (NMN/NaMN adenylyltransferase 1)|Nicotinamide-nucleotide adenylyltransferase 1 (NMN adenylyltransferase 1)|Nicotinate-nucleotide adenylyltransferase 1 (NaMN adenylyltransferase 1)|NMNAT1|NMNAT antibody
Isotype
IgG
Form
liquid
Purification
Immunogen affinity purified
Immunogen
nicotinamide nucleotide adenylyltransferase 1
Recommended dilution
WB: 1:500-1:2000; IHC: 1:20-1:200
Purity
≥95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Background
Catalyzes the formation of NAD(+) from nicotinamide mononucleotide(NMN) and ATP(PubMed:17402747). Can also use the deamidated form; nicotinic acid mononucleotide(NaMN) as substrate with the same efficiency(PubMed:17402747). Can use triazofurin monophosphate(TrMP) as substrate(PubMed:17402747). Also catalyzes the reverse reaction, i.e. the pyrophosphorolytic cleavage of NAD(+)(PubMed:17402747). For the pyrophosphorolytic activity, prefers NAD(+) and NaAD as substrates and degrades NADH, nicotinic acid adenine dinucleotide phosphate(NHD) and nicotinamide guanine dinucleotide(NGD) less effectively(PubMed:17402747). Involved in the synthesis of ATP in the nucleus, together with PARP1, PARG and NUDT5(PubMed:27257257). Nuclear ATP generation is required for extensive chromatin remodeling events that are energy-consuming(PubMed:27257257). Fails to cleave phosphorylated dinucleotides NADP(+), NADPH and NaADP(+)(PubMed:17402747). Protects against axonal degeneration following mechanical or toxic insults(By similarity).


Figures for this product are not available in this catalogue.

Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Dispatch Time
About 3 working days
Ordering & Delivery
How do I place an order?
Use the Inquiry button on this page or write to tekintolga89@gmail.com. Include the catalogue number and the quantity you need.
What is the dispatch time?
In-stock items are dispatched within 1-3 business days. Items that need to be produced take longer; we confirm the date when you order.
Do you ship outside Türkiye?
Shipping is arranged case by case. Contact us with the destination and we will quote carriage and lead time.
Storage & Handling
How should an unopened kit be stored?
At 2-8 °C unless the datasheet says otherwise. Do not freeze a kit that is not marked for freezing.
How long is an opened kit stable?
It depends on the component. The Kit Components table on this page lists the storage condition for each item after opening.
What should I do if the shipment arrives warm?
Photograph the package and contact us the same day. Do not use the kit until we have confirmed it is still within specification.
Assay Questions
Which sample types can I use?
The Sample Type row in the specifications above lists the validated matrices for this product. Other matrices need validation on your side.
My background is too high. What should I check?
The usual causes are insufficient washing, contaminated buffers, or too much detection antibody. Our Protocol pages cover the full troubleshooting sequence.
Can I run fewer wells than the kit provides?
Yes. Dismountable microplates let you use part of a plate and reseal the rest with the desiccant supplied.
Technical Support
Something did not work. What do you need from me?
Send the catalogue number, the lot, your protocol deviations and the raw OD values. That is usually enough to identify the cause.
Do you provide a certificate of analysis?
Yes, per lot. Ask for it with the catalogue number and lot number.

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Cited Publications (1)

KNOP1 interacts with NMNAT1 to govern ferroptosis and tumor growth in breast cancer via regulating FoxO1-dependent GPX4 transcription IF: 3.7

Cellular Signalling · 2025-08-15

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