ALKBH7 antibody

Category:
Catalogue No.: 
FNab00315
Alias: 
Alpha-ketoglutarate-dependent dioxygenase alkB homolog 7 antibody, mitochondrial|Alkylated DNA repair protein alkB homolog 7|Spermatogenesis cell proliferation-related protein|Spermatogenesis-associated protein 11|ALKBH7|ABH7|SPATA11 antibody
Gene Name: 
ALKBH7
UniProt ID: 
Q9BT30
Size Price
100μg Inquiry
Dispatch Time: About 3 working days
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Product Name
ALKBH7 antibody
Catalogue No.
FNab00315
Gene Name
ALKBH7
UniProt ID
Q9BT30
Alias
Alpha-ketoglutarate-dependent dioxygenase alkB homolog 7 antibody, mitochondrial|Alkylated DNA repair protein alkB homolog 7|Spermatogenesis cell proliferation-related protein|Spermatogenesis-associated protein 11|ALKBH7|ABH7|SPATA11 antibody
Isotype
IgG
Form
liquid
Purification
Immunogen affinity purified
Immunogen
alkB, alkylation repair homolog 7(E. coli)
Recommended dilution
WB: 1:200-1:2000; IHC: 1:20-1:200
Purity
≥95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Background
May function as protein hydroxylase; can catalyze auto-hydroxylation at Leu-110(in vitro), but this activity may be due to the absence of the true substrate(PubMed:25122757). Required to induce programmed necrosis in response to DNA damage caused by cytotoxic alkylating agents. Acts by triggering the collapse of mitochondrial membrane potential and loss of mitochondrial function that leads to energy depletion and cell death(PubMed:23666923). ALKBH7-mediated necrosis is probably required to prevent the accumulation of cells with DNA damage(PubMed:23666923). Does not display DNA demethylase activity(PubMed:23666923). Involved in fatty acid metabolism(By similarity).


Figures for this product are not available in this catalogue.

Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Dispatch Time
About 3 working days
Ordering & Delivery
How do I place an order?
Use the Inquiry button on this page or write to tekintolga89@gmail.com. Include the catalogue number and the quantity you need.
What is the dispatch time?
In-stock items are dispatched within 1-3 business days. Items that need to be produced take longer; we confirm the date when you order.
Do you ship outside Türkiye?
Shipping is arranged case by case. Contact us with the destination and we will quote carriage and lead time.
Storage & Handling
How should an unopened kit be stored?
At 2-8 °C unless the datasheet says otherwise. Do not freeze a kit that is not marked for freezing.
How long is an opened kit stable?
It depends on the component. The Kit Components table on this page lists the storage condition for each item after opening.
What should I do if the shipment arrives warm?
Photograph the package and contact us the same day. Do not use the kit until we have confirmed it is still within specification.
Assay Questions
Which sample types can I use?
The Sample Type row in the specifications above lists the validated matrices for this product. Other matrices need validation on your side.
My background is too high. What should I check?
The usual causes are insufficient washing, contaminated buffers, or too much detection antibody. Our Protocol pages cover the full troubleshooting sequence.
Can I run fewer wells than the kit provides?
Yes. Dismountable microplates let you use part of a plate and reseal the rest with the desiccant supplied.
Technical Support
Something did not work. What do you need from me?
Send the catalogue number, the lot, your protocol deviations and the raw OD values. That is usually enough to identify the cause.
Do you provide a certificate of analysis?
Yes, per lot. Ask for it with the catalogue number and lot number.

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